Now showing items 1-15 of 15

    • Husen, Peter; Fidorra, Matthias; Härtel, Steffen; Bagatolli, Luis A.; Ipsen, Jhon H. (Springer, 2011-11-09)
      Quantitative characterization of the lateral structure of curved membranes based on fluorescence microscopy requires knowledge of the fluorophore distribution on the surface. We present an image analysis approach for ...
    • Zomosa Rojas, Gustavo (Universidad de Chile, 2017)
      En agosto de 2015, el Ministerio de Salud de Chile (MINSAL) levanta su cuarta licitación para contratación de Servicios de Teleradiología (TR), que contenía exigencias de software de gestión y la posibilidad del uso de ...
    • Miranda Ruiz, Felipe Ignacio (Universidad de Chile, 2020)
      Cervical Intraepithelial Neoplasia (CIN) is a precancerous state of the cervix, and the correct diagnosis of its level of severity (CIN grade) allows to determine patient treatment and prevent invasive carcinoma. It ...
    • Urra, Hery; Torres Gómez, Vicente; Ortiz, Rina J.; Lobos, Lorena; Díaz, María I.; Díaz, Natalia; Härtel, Steffen; Leyton Campos, Lisette; Quest, Andrew F. G. (PUBLIC LIBRARY SCIENCE, 2012-04-10)
      Caveolin-1 is known to promote cell migration, and increased caveolin-1 expression is associated with tumor progression and metastasis. In fibroblasts, caveolin-1 polarization and phosphorylation of tyrosine-14 are essential ...
    • Bahamondes, Verónica; Albornoz, Amelina; Aguilera, Sergio; Alliende, Cecilia; Molina, Claudio; Castro, Isabel; Urzúa Tobar, Ulises; Quest, Andrew F. G.; Barrera, María José; González, Sergio; Sánchez, Marianela; Härtel, Steffen; Hermoso Ramello, Marcela; Leyton Martínez, Cecilia; González Burgos, María Julieta (WILEY-BLACKWELL, 2011-10)
      Objective. Oral and ocular dryness are frequent and serious symptoms of Sjogren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...
    • Colombo, Alicia; Palma, Karina; Armijo, Lorena; Mione, Marina; Signore, Iskra A.; Morales, Camila; Guerrero, Néstor; Meynard, Margarita M.; Pérez, Ramón; Suazo, José; Marcelain Cubillos, Katherine; Briones, Luis; Härtel, Steffen; Wilson, Stephen W.; Concha Nordemann, Miguel (The Company of Biologists, 2013)
      Although progress has been made in resolving the genetic pathways that specify neuronal asymmetries in the brain, little is known about genes that mediate the development of structural asymmetries between neurons on left ...
    • Lopez Cayo, Jimena Victoria (Universidad de Chile, 2017)
      El advenimiento de la Patología Digital (PD) y la creación de placas virtuales ofrecen nuevas posibilidades para el procesamiento, análisis e interpretación de imágenes que se suman al creciente interés en la cuantificación ...
    • Riquelme, Denise; Álvarez, Alvaro; Leal, Nancy; Adasme, Tatiana; Espinoza, Italo; Valdés, Juan Antonio; Troncoso, Natalia; Härtel, Steffen; Hidalgo Tapia, Jorge; Hidalgo Tapia, María Cecilia; Carrasco Friz, María Angélica (2011)
      Neuronal electrical activity increases intracellular Ca2+ concentration and generates reactive oxygen species. Here, we show that high frequency field stimulation of primary hippocampal neurons generated Ca2+ signals with ...
    • Richardson, Jo; Gauert, Anton; Briones Montecinos, Luis; Kabla, Alexandre; Härtel, Steffen; Linker, Claudia (Cell Press, 2016)
      Collective cell migration is fundamental for life and a hallmark of cancer. Neural crest (NC) cells migrate collectively, but the mechanisms governing this process remain controversial. Previous analyses in Xenopus indicate ...
    • Ramírez, Omar A.; Härtel, Steffen; Couve Correa, Andrés (SOC BIOLGIA CHILE, 2011)
      Neurons are highly polarized, but the trafficking mechanisms that operate in these cells and the topological organization of their secretory organelles a re still poorly understood. Particularly incipient is our knowledge ...
    • Delpiano Costabal, José; Jara, Jorge; Scheer, Jan; Ramírez, Omar A.; Ruiz del Solar, Javier; Härtel, Steffen (Springer, 2012)
      Optical flow approaches calculate vector fields which determine the apparent velocities of objects in timevarying image sequences. They have been analyzed extensively in computer science using both natural and ...
    • Busso, Dolores; Oñate Alvarado, María José; Balboa, Elisa; Castro, Juan; Lizama, Carlos; Morales, Gabriela; Vargas, Susana; Härtel, Steffen; Moreno, Ricardo D.; Zanlungo, Silvana (CSIRO, 2014)
      The cholesterol content of the sperm membrane is regulated during both maturation in the epididymis and capacitation in the female tract, two processes required for the spermatozoa to acquire their fertilising ability. ...
    • Maturana, J.; Niechi, I.; Silva, E.; Huerta, H.; Cataldo, R.; Härtel, Steffen; Barros, L.; Galindo Díaz, Mario; Tapia Pineda, Julio (Elsevier, 2015)
      The key protein in the canonicalWnt pathway is β-catenin, which is phosphorylated both in absence and presence ofWnt signals by different kinases. Upon activation in the cytoplasm, β-catenin can enter into the nucleus ...
    • Liempi, Ana; Castillo, Christian; Cerda, Mauricio; Droguett, Daniel; Duaso, Juan; Barahona, Katherine; Hernández, Ariane; Díaz Luján, Cintia; Fretes, Ricardo; Härtel, Steffen; Kemmerling Weis, Ulrike (Elsevier, 2015)
      Chagas disease is an endemic, neglected tropical disease in Latin America that is caused by the protozoan parasite Trypanosoma cruzi. In vitro models constitute the first experimental approach to study the physiopathology ...
    • Liempi Manquel, Ana; Castillo, Christian; Cerda Villablanca, Mauricio; Droguett Ossa, Daniel; Duaso, Juan; Barahona, Katherine; Hernández, Ariane; Díaz Luján, Cintia; Fretes, Ricardo; Härtel, Steffen; Kemmerling Weis, Ulrike (Elsevier, 2015)
      Chagas disease is an endemic, neglected tropical disease in Latin America that is caused by the protozoan parasite Trypanosoma cruzi. In vitro models constitute the first experimental approach to study the physiopathology ...